High Risk Clinic

1. Do you have a family or personal history of any of the following:

• Breast Cancer before age 50?

• Breast cancer in two or more close relatives*?

• Breast cancer in male relative?

• Breast cancer in both breasts or twice in the same breast?

• Breast cancer and Ashkenazi, or Eastern European Jewish, ancestry?

• Ovarian cancer at any age?

Yes No

2. Do you have a family member who has a known mutation in BRCA1, BRCA2 or another breast cancer susceptibility gene?

Yes No

3. Do you have a BRCA1 or BRCA2 gene mutation?

Yes No

4. Do you have a history of biopsy-proven atypical ductal hyperplasia (ADH), atypical lobular hyperplasia (ALH) or lobular carcinoma in situ (LCIS)?

Yes No

5. Have you had chest wall radiation (for example, in treatment for Hodgkin’s disease) between ages 10 and 30?

Yes No

6. Are you 35 years of age or older with a modified Gail 5-year risk for invasive breast cancer > 1.7%? (To determine your Gail risk please use the National Cancer Institute Breast Cancer Risk Assessment Tool.)

Yes No

*Definition of close relatives: mother, father, sister, brother, daughter, son, aunt, uncle, grandmother, grandfather, granddaughter, grandson, niece, nephew, half-brother, and half-sister.

If you answered Yes to any of the above questions, You may be at a high risk for Breast Cancer.

High Risk Assessment Team

Surgical Oncology
Sheryl G.A. Gabram, MD
Monica Rizzo, MD
Toncred Marya Styblo, MD

Genetic Counselors
Amanda Eppolito, MS, CGC
Carrie A. Crain, MS
Christine Stanislaw, MS, CGC

Medical Oncology
Navneet Dhillon, MD
Sujatha Murali, MD
Ruth M. O'Regan, MD
Amelia Zelnak, MD
Kandra Horne, NP

Gynecologic Oncology
Lisa Flowers, MD
Namita Khanna, MD
Dana M. Meaney-Delman, MD

Genetic Counseling and Testing

A genetic counseling visit includes a review of family history, personalized risk assessment and discussion of surveillance and genetic testing options.

Approximately five to 10 percent of breast cancer cases are hereditary, or due to gene mutations that can be passed down in a family. The two genes most commonly associated with hereditary breast cancer are BRCA1 and BRCA2 (BReast CAncer genes 1 and 2).

The function of these genes is to help keep breast cells growing normally. Mutations (changes or alterations) in BRCA1 and BRCA2 are associated with an increased risk of developing breast cancer, including early onset breast cancer. BRCA1 and BRCA2 mutations also increase the risk for ovarian cancer in women and male breast cancer and early-onset prostate cancer in men.

For more information on genetics, please visit the Emory Department of Human Genetics.