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Sharmila Makhija, M.D.
The Emory Clinic
Associate Professor of Gynecology and Obstetrics
Chief of Gynecologic Oncology


Specialties
Obstetrics and Gynecology (Board certified since 2001)
Gynecologic Oncology (Board certified since 2003)

Area of Clinical Interest
cervical cancer
ovarian cancer
uterine cancer


Hospital Affiliation(s)
Emory University Hospital

Addresses Locations

The Emory Clinic 'A'
1365 Clifton Road, NE
Atlanta , GA 30322 Map to the office
(404) 778-3401


Year started practicing at Emory
2008

Education
Medical School
University of Alabama School of Medicine, Birmingham, AL 1992

Residency
University of Louisville Hospital, Louisville, KY 1996

Fellowship
Memorial Sloan-Kettering Cancer Center, New York, NY 1999

Organizational Leadership Memberships
American College of Obstetrics and Gynecology

American Society of Clinical Oncology

American Society of Gene Therapy

HIV Prevention Trials Network

International Society of Gynecologic Cancer

Society of Gynecologic Oncologists



Awards
Atlanta Magazine Top Doctors 2009
Georgia Cancer Coalition,
Distinguished Clinician Scientist 2008

Major or Recent Publications
Li Y, Wang H, Wang Z, Makhija S, Buchsbaum D, LoBuglio A, Kimberly R, Zhou T. Inducible Resistance of Tumor Cells to Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Receptor 2-Mediated Apoptosis by Generation of a Blockade at the Death Domain Function . Cancer Res 2006 Sep,66(17): 8520-8528.

Numnum TM, Makhija S, Lu B, Wang M, Rivera A, Stoff-Khalili M, Alvarez RD, Zhu ZB, Curiel DT Improved anti-tumor therapy based upon infectivity-enhanced adenoviral delivery of RNA interference in ovarian carcinoma cell lines. Gynecol Oncol. 2008 Jan,108(1):34-41. Epub 2007 Dec 3.

Page JG, Tian B, Schweikart K, Tomaszewski J, Harris R, Broadt T, Polley-Nelson J, Noker PE, Wang M, Makhija S, Aurigemma R, Curiel DT, Alvarez RD. Identifying the Safety Profile of a Novel Infectivity-Enhanced Conditionally Replicative Adenovirus, Ad5-delta24-RGD, in Anticipation of a Phase I trial for Recurrent Ovarian Cancer . Am J Obstet Gynecol,2007 Apr; 196(4):389, 1-9.

Rocconi R, Numnum M, Zhu A, Lu Baogen, Wang M, Rivera A, Stoff-Khalili M, Alvarez R, Curiel DT, Makhija S. Icodextrin Enhances Survival in an Intraperitoneal Ovarian Cancer Murine Model Utilizing Gene Therapy. Gynecol Oncol,2006.

Rocconi RP, Zhu ZB, Stoff-Khalili M, Rivera AA, Lu B, Wang M, Alvarez RD, Curiel DT, Makhija S. Treatment of Ovarian Cancer with a Novel Dual Targeted Conditionally Replicative Adenovirus (CRAd) . Gynecol Oncol,2007 Apr; 105(1): 113-21.

Zhu Z, Makhija SK, Lu B, Wang M, Rivera A, Kim-Park S, Ulasov I, Zhou F, Alvarez RD, Siegal G, Curiel DT. Incorporating the Survivin Promoter in an Infectivity Enhanced CRAd-Analysis of Oncolysis and Anti-tumor Effects in vitro and in vivo . Int J Oncol. 2005 Jul,27(1):237-46.

Zhu ZB, Chen Y, Makhija S, Lu B, Wang M, Rivera AA, Yamamoto M, Wang S, Siegal GP, Curiel DT, McDonald JM. Survivin promoter-based conditionally replicative adenoviruses target cholangiocarcinoma. Int J Oncol. 2006 Nov,29(5):1319-29.

Zhu ZB, Lu B, Park M, Makhija S, Numnum T, Kendrick J, Wang M, Tsuruta Y,Fisher P, Alvarez RD, Zhou F, Siegal G, Wu H, Curiel DT. Development of an Optimized Conditionally Replicative Adenoviral Agent For Ovarian Cancer. Int J Oncol,2008.

Zhu ZB, Makhija S, Lu B, Wang M, Wang S, Takayama K, Siegal GP, Reynolds PN, Curiel DT. Targeting Mesothelioma Using an Infectivity Enhanced Survivin-Conditionally Replicative Adenoviruses . J Thorac Oncol, 2006 Sep,1(7):701-11.

Zhu ZB, Mathis M, Makhija S, Lu B, Wang M, Ji S, Rivera AA, Rosenthal EL, Siegal GP, Curiel DT. Targeting of a conditionally replicative adenovirus agent to human squamous cell carcinomas of the head and neck . Int J Oncol. 2007 Nov,31(5):1213-22.

Zhu ZB, Rivera AA, Makhija S, Lu B, Wang M, Izumi M, Cerfolio RJ, Stoff-Khalili MA, Zhou F, Takayama K, Siegal GP, Curiel DT. Targeting Lung Cancer Using an Infectivity Enhanced CXCR4-CRAd. Lung Cancer,2007 Feb; 55(2):145-56.