Adriana Ioachimescu, MD, PhD, FACE

 

Adriana Ioachimescu Adriana Ioachimescu, MD, PhD, FACE
Co-Director, Emory Neuroendocrine Pituitary Center
Associate Professor, Departments of Medicine and Neurosurgery

The Emory Clinic, Building B, 6th floor
1365 Clifton Rd., NE, Ste. 6200
Atlanta, GA 30322

To make an appointment: 404-778-5770

Dr. Ioachimescu graduated from Carol Davila University of Medicine in Bucharest, Romania. She underwent postgraduate training in Europe in Internal Medicine and Endocrinology, focusing on pituitary diseases. Dr. Ioachimescu earned a PhD in Neuroendocrinology from the same university in 2001, then completed additional training in Internal Medicine and Endocrinology at Yale University and the Cleveland Clinic. Dr. Ioachimescu was a member of the faculty at the Cleveland Clinic before joining Emory University.

Dr. Ioachimescu's clinical activities focus on diagnosis and endocrine management of pituitary diseases. She is Co-Director of the Emory Neuroendocrine Pituitary Center, a premier tertiary center for neuroendocrine care for patients with pituitary tumors. She oversees the activity of the neuroendocrine clinic. Dr. Ioachimescu works together with Dr. Nelson Oyesiku and a team of radiation specialists to provide streamlined, comprehensive care for pituitary patients.

Dr. Ioachimescu's research focuses on pituitary tumors pathogenesis and outcomes, with the purpose of validation of prognostic markers and identification of novel therapies for pituitary tumors.

Areas of Clinical Expertise:

  • Pituitary tumors
  • Pituitary hormone deficiencies
  • Cushing's Syndrome
  • Acromegaly
  • Hyperprolactinemia
  • Adrenal Gland Tumors

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Society Memberships:

  • Endocrine Society
  • Pituitary Society
  • American Association of Clinical Endocrinologists - Member of Board of Directors of the Georgia Chapter
  • American Diabetes Association
  • Southern Society for Clinical Investigation
  • American Federation for Medical Research in Medicine (AFMR), President of the Southern AFMR and National Councilor of the AFMR"

Honors

  • June 2010: Mentor of the Year Award, chosen by endocrine fellows in the Division of Endocrinology and Metabolism
  • May 2010: Nominated for the Emory Department of Medicine Outstanding Scientific Citation
  • April 2010: Elected Fellow of the American College of Endocrinology
  • April 2008: Mara Lieberman Award, Endocrine Society for the abstract “The Lipid Accumulation Product and not BMI is associated with all-cause mortality in patients at high risk of cardiovascular diseases”
  • May 2006: American Association of Clinical Endocrinologists (AACE) Young Investigator Award (First Prize) for the oral
  • presentation: “Immunologic thrombocytopenia is associated with increased prevalence of thyroid disease but is not impacted by thyroid treatment – a longitudinal retrospective study”
  • May 2005: AACE Young Investigator Award (Honorable mention) for the oral presentation “Thrombocytopenia in Autoimmune Thyroid Disease: Case Presentations and Review of the literature”
  • May 2002: Joseph Belski Research Day, 3rd prize Clinical Section for the poster “Pituitary Hypophysitis Requiring Repeated Surgery (a case report)”
  • May 2002: Joseph Belski Research Day, 3rd prize Research Section for the poster “Neurohormones involved in sleep-wake cycle - in vitro electrophysiological testing of somatostatin effects on thalamic habenular neurons in rodents”

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Grants

  • Dec 2011: Investigator intiated research: Calcium Homeostasis in Acromegaly
  • Sept 2009: Investigator-initiated research: Growth hormone deficiency in veterans with history of traumatic brain injury
  • May 2005: Endocrine Fellows Foundation Research Grant for the project “Plasma Free Fatty Acids, Endothelial Dysfunction, and the Role of Nitric Oxide Synthase (NOS) Pathway in Subjects With and Without Insulin Resistance”
  • June 1999: Romanian Society of Psychoneuronendocrinology Annual Research Grant for the project “Vasotocin effects on dorsal raphe nuclei – in vitro electrophysiology study”
  • June 1997: Romanian Society of Psychoneuronendocrinology Annual Research Grant for the project “Vasotocin effects on habenular nuclei – in vitro electrophysiology study”

Original Articles

Silent corticotroph adenomas: Emory University cohort and comparison with ACTH-negative nonfunctioning pituitary adenomas. Ioachimescu AG, Eiland L, Chhabra VS, Mastrogianakis GM, Schniederjan MJ, Brat D, Pileggi AV, Oyesiku NM. Neurosurgery. 2012 Aug;71(2):296-303

Ioachimescu AG, Hamrahian AH, Stevens M, Zimmerman R. The Pituitary Stalk Transection Syndrome: Multifaceted Presentation in Adulthood. Pituitary – 2011 Aug 9. [Epub ahead of print]

Ioachimescu AG, Hamrahian AH, Stevens M, Zimmermam RS. The Pituitary Stalk Transection Syndrome: Multifaceted Presentation in Adulthood. Pituitary, 2011, in press

Shah R, Licata A, Oyesiku NM, Ioachimescu AG. Acromegaly as a cause of 1,25-dihydroxy-vitamin D dependent hypercalcemia: case reports and review of literature. Pituitary. Published online December 28, 2010

Pantalone KM, Gopan T, Remer EM, Faiman C, Ioachimescu AG, Levin HS, Siperstein A, Berber E, Shepardson LB, Bravo EL, Hamrahian AH.Change in adrenal mass size as a predictor of malignancy. Endocrine Practice, Feb 2010, pg 1-31

Ioachimescu AG, Brennan D, Hoar B, Hoogwerf BJ. The lipid accumulation product and all-cause mortality in patients at high cardiovascular risk: a PreCIS cohort study. Obesity, Dec 24, 2009 (Epub ahead of print)

Ioachimescu AG, Brennan DM, Hoar BM, Hazen SL, Hoogwerf BJ. Serum uric acid is an independent predictor of all-cause mortality in patients at high risk of cardiovascular disease: A preventive cardiology information system (PreCIS) database cohort study. Arthritis Rheum. 2008 Jan 31;58(2):623-630

Ioachimescu AG, Brennan DB, Hoar BM, Kashyap SR, Hoogwerf BJ. Serum uric acid, mortality and glucose control in patients with type 2 diabetes mellitus: a PreCIS data base study. Diabet Med. 2007 Dec;24(12):1369-74.

Ioachimescu AG, Makdissi A, Lichtin A, Zimmerman R. Thyroid disease in patients with idiopathic thrombocytopenia - a cohort study. Thyroid. 2007 Nov;17(11):1137-42.

Tamaskar I, Bukowski R, Elson P, Ioachimescu AG, Wood L, Dreicer R, Mekhail T, Garcia J, Rini BI. Thyroid function test abnormalities in patients with metastatic renal cell carcinoma treated with sorafenib. Ann Oncol. 2007 Oct 24; [Epub ahead of print]

Hamrahian AH, Ioachimescu AG, Remer EM, Motta-Ramirez G, Bogabathina H, Levin HS, Reddy S, Gill IS, Siperstein A, Bravo EL. Clinical Utility of Noncontrast CT Attenuation Value (HU) to Differentiate Adrenal Adenomas/Hyperplasias from Nonadenomas: Cleveland Clinic Experience. J Clin Endocrinol Metab. 2005 Feb; 90(2):871-7

Ioachimescu OC, Ioachimescu AG, Iannini PB. Severity scoring in community-acquired pneumonia caused by Streptococcus pneumoniae: a 5-year experience. Int J Antimicrob Agents. 2004 Nov; 24(5):485-90

Ioachimescu AG. Somatostatin receptors in thalamic habenula - in vitro electrophysiology study. Romanian Journal of Endocrinology, 1998, vol. 3-4

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Book & Online Chapters

Ioachimescu AG and Constantin T. Endocrine Disorders and Mental Health in The Hormone Factor in Mental Health. Bridging the Mind-Body Gap. Editor Linda M Rio. Jessica Kingsley Publishers, London, UK. 2013.

Miller BA, Rutledge WC, Ioachimescu AG, Oyesiku NM. Management of Large Aggressive Nonfunctional Pituitary Tumors: Experimental Medical Options when Surgery and Radiation Fail in Neurosurgery Clinics of North America. Management of Pituitary Tumors. Editors Aghi MK, Blevins LS, Volume 23, Number 4. WB Saunders Company, Philadelphia, 2012.

Muh C, Ioachimescu AG, Oyesiku NM. Growth Hormone Secreting Tumors in Schmidek & Sweet’s Operative Neurosurgical Techniques: Indications, Methods and Results, 6th Edition. Editor A Quinones-Hinojosa, Volume 1, Chapter 18, Elsevier/Saunders, Philadelphia, 2012. 

Ioachimescu AG. Glucocorticosteroids. In: ASAP - American College of Endocrinology (ACE) Self Assessment Program [online]. 2011. Available at: http://asap.aace.com.

Muh C, Ioachimescu AG, Oyesiku NM. Chapter 18: Growth Hormone Secreting Tumors in Schmidek & Sweet’s Operative Neurosurgical Techniques, 6th Edition; 2011.

Ioachimescu AG and Hamrahian AH. Diseases of the Adrenal Gland, chapter in 2009 Current Clinical Medicine. An Expert Consult Title. Editor William D. Carey. Saunders Elsevier, 2009

Ioachimescu AG, Hamrahian AH. Acute Adrenal Insufficiency in Critical Care Diagnosis and Treatment. Pulmonary and Critical Care Update (PCCU), volume 20, lesson 16, July 2006

Case Reports

Visual Vignette. Giant internal carotid artery aneurysm presenting as a suprasellar mass. Ioachimescu AG, Eiland L, Barrow DL. Endocrine Practice 2013 Sep 6:1-7.

Transformation of a Silent Adrencorticotrophic Pituitary Tumor Into Central Nervous System Melanoma. Brandon A. Miller, Tomoko Tanaka, Adriana G. Ioachimescu, Cristina Vincentelli, Christina L. Appin, Nelson M. Oyesiku. Journal of Investigative Medicine High Impact Case Reports April-June 2013 vol. 1 no. 2

Pituitary carcinoma in situ. Pasquel FJ, Vincentelli C, Brat DJ, Oyesiku NM, Ioachimescu AG. Endocr Pract. 2013 May-Jun;19(3):e69-73. doi: 10.4158/EP12351.CR.

Eiland L, Oyesiku NM, Ritchie JC, Isaacs S, Ioachimescu AG. Pathogenesis of Marked Pituitary Enlargement and Increased Serum Thyroid-Stimulating Hormone in Primary Hypothyroidism. Thyroid. 2011 Dec 7.

Shah R, Schniederjan M, DelGaudio JM, Ioachimescu AG. Visual vignette. Cushing’s Syndrome Due to an Ectopic Clival Pituitary Adenoma. Endocrine Practice 2011 Nov 1;17(6):966.

Srivatsa S, Ioachimescu AG, Oyesiku NM, Hunter S. Pituicytoma – a visual vignette. Endocrine Practice, 14 (9), pg 1192, 2008.

Ioachimescu AG, Bauer TW, Licata A. Active Crohn's Disease as a Cause for Hypercalcemia, which Responded to Infliximab: Case Presentation and Review of Literature. Endocrine Practice. Endocr Pract. 2008 Jan-Feb;14(1):87-92.

Ioachimescu O, Ioachimescu A, Badiu C, Calt C, Galbenu P, Stoicescu P, Coculescu M: Endocrine symptoms = Endocrine pathology? - Case presentation. Romanian Journal of Endocrinology, 1998, vol. 3-4

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Review Articles

 Management of large aggressive nonfunctional pituitary tumors: experimental medical options when surgery and radiation fail. Miller BA, Rutledge WC, Ioachimescu AG, Oyesiku NM. Neurosurg Clin N Am. 2012 Oct;23(4):587-94. doi: 10.1016/j.nec.2012.06.013.

Ioachimescu AG, Bauer TW, Licata A. Active Crohn’s Disease as a Cause for Hypercalcemia, which Responded to Infliximab: Case Presentation and Review of Literature. Endocrine Practice, 14, pg 87-92, 2008.

Ioachimescu AG and Licata A. Etidronate: What is its place in treatment of primary osteoporosis and other demineralizing diseases today? Current Osteoporosis Reports. 2007 Dec, 5:165-169.

Ioachimescu AG and Licata A. Treatment of osteoporosis in postmenopausal women who are at risk for fractures. US Endocrine Disease, 2007 Jan; issue 2: 119-121.

Ioachimescu AG, Hamrahian AH. Acute Adrenal Insufficiency in Critical Care Diagnosis and Treatment. Pulmonary and Critical Care Update (PCCU), volume 20, lesson 16, July 2006.

Ioachimescu AG. Pineal gland and sleep. Sibiul Medical, 2000, 11:8-14.

Teaching/Education

Course Director

Sept 2013: The Emory Pituitary Education Day for patients, family, and friends.

April 2011: Emory Pituitary Day. A course for patients, family, and friends.

October 2011 & 2008: Emory Pituitary Day. A case-based update on pituitary disorders. CME activity for physicians who treat pituitary disorders.

Course Faculty

Pituitary Hormone Replacement in Women, Pituitary Network Association webinar, Aug 2013

Cleveland Clinic 8th Annual Pituitary Conference, “Acromegaly, Case Discussion”, Sept 2012

Carolinas Chapter of the American Association of Clinical Endocrinologists, “Pituitary Surgery for and Medical Treatment of Acromegaly”, oral presentation, 2012

October 2011: Emory Pituitary Day A case-based update on pituitary disorders (topic: Corticotrophy adenomas)

June 2009: Intraventricular and skull-based neuro-endoscopy course at Emory University (topic: Neuroendocrinology).

October 2008: Emory Pituitary Day. A case-based update on pituitary disorders (topic: Hyperprolactinemia).

August 2011, 2010, 2009 and 2008: Emory University Internal Medicine Board Review Course (topic: Pituitary and Adrenal Disorders).

Media/Press Releases

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