Jeffrey J. Olson, MD

 Jeffrey J. Olson

Jeffrey J. Olson, MD
Professor, Department of Neurosurgery
Professor, Department of Hematology and Medical Oncology
Director, Neurosurgical Oncology Fellowship
Director, Clinically-related Neuro-oncology Laboratory
Co-director, Brain Tumor Program

The Emory Clinic, Building B, 2nd floor
1365-B Clifton Rd., NE, Ste. 2200
Atlanta, GA 30322

To make an appointment: 404-778-5770

Dr. Olson received his MD from the University of Minnesota and completed his neurosurgical residency training at the University of Iowa. He spent three years as a Senior Staff Fellow at the National Institutes of Health in Bethesda, Maryland. In 1990, Dr. Olson joined the faculty of Emory University's School of Medicine, where he continues to practice as a renowned neurosurgeon and professor of Neurosurgery, Hematology and Medical Oncology. He is also Principal Investigator for Emory for the National Cancer Institute Sponsored Adult Brain Tumor Consortium. In 2010, Dr. Olson was named President of the Georgia Neurosurgical Society.

Dr. Olson's primary interest is in neuro-oncology, also known as brain cancer. His neurosurgical practice and research involve the biology and therapy of brain tumors, and his primary area of research is clinical trials of new brain tumor therapies.

Clinical Trials

Dr. Olson's research is an important resource for patients who wish to participate in clinical trials for malignant brain tumors. Emory's multidisciplinary neuro-oncology team offers patients the option to participate in research studies that use a variety of innovative approaches for treating the molecular and anatomic characteristics of brain tumors. Professionals with basic science, medical oncology, neurology, radiology, radiation oncology and neurosurgical backgrounds collaborate to provide patients the best exposure to a range of treatment options. Learn more about clinical trials at Emory.

Areas of Clinical Interest:

  • clinical brain tumor research including studies to improve surgery, chemotherapy, radiation and brain tumor imaging
  • acoustic neuroma
  • glionblastoma (Emory PI for the NCI-sponsored New Approaches to Brain Tumor Therapies-CNS Consortium)
  • low grade gliomas
  • meningiomas
  • metastatic brain tumors
  • cerebrospinal fluid leakage
  • cranial nerve disorder
  • lesions of the anterior and posterior skullbase
  • stereotactic surgery and radiosurgery

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Peer Reviewed Publications

Wang L, Chen D, Yang X, Olson JJ, Gopinath K, et al. Group Independent Component Analysis and Functional MRI Examination of Changes in Language Areas Associated with Brain Tumors at Different Locations. PLoS ONE 8(3): e59657. doi:10.1371/journal.pone.0059657, 2013.

Amankwah EK. Thompson RC. Nabors LB. Olson JJ. Browning JE. Madden MH. Egan KM:  SWI/SNF gene variants and glioma risk and outcome.  Cancer Epidemiology. 37(2):162-5, 2013.

Appin CL, Gao J, Chisolm C, Torian M. Alexis ,. Vincentelli C, Schniederjan MJ, Hadjipanayis C, Olson JJ, Hunter S, Hao C, Brat DJ:  Glioblastoma with oligodendroglioma component (GBM-O): molecular genetic and clinical characteristics. Brain Pathology. 23(4):454-61, 2013. 

Press RH, Prabhu RS, Appin CL, Brat DJ, Shu HK, Hadjipanayis C, Olson JJ, Oyesiku NM, Curran WJ, Crocker I:  Outcomes and Patterns of Failure for Grade II Meningioma Treated With Reduced Margin Intensity Modulated Radiation Therapy. Int J Radiat Oncol Biol Phys. 88:1004-10, 2014. 

Olson JJ:  Glioblastoma at progression: therapy of a challenging problem addressed candidly with evidence-based techniques.  Journal of Neuro-oncology, 118: 427-428, 2014

Olson JJ, Ryken, TC, Kalkanis, SN:  The Management of Progressive Glioblastoma: A Systematic Review and Evidence-Based Clinical Practice Guideline: Introduction and Rationale.  Journal of Neuro-oncology, 118: 429-434, 2014

Ryken CR, Aygun N, Morris J, Schweizer M, Nair R, Spracklen C, Kalkanis SH, Olson JJ:  The Role of Imaging in the Management of Progressive Glioblastoma.  Journal of Neuro-oncology, 118: 435-460, 2014.

Brat DJ, Ryken TC, Kalkanis SN, Olson JJ:  The Role of Neuropathology in the Management of Progressive Glioblastoma.  Journal of Neuro-oncology, 118: 461-478, 2014.

Ryken TC, Kalkanis SN, Buatti JM, Olson JJ:  The Role of Cytoreductive Surgery in the Management of Progressive Glioblastoma.  Journal of Neuro-oncology, 118: 479-488, 2014.

Ryu S, Buatti JM, Morris A, Kalkanis SN, Ryken TC, Olson JJ:  The Role of Radiotherapy in the Management of Progressive Glioblastoma.  Journal of Neuro-oncology, 118: 489-499, 2014.

Olson JJ, Nayak L, Ormond DR, Wen PY, Kalkanis SN:  The Role of Cytotoxic Chemotherapy in the Management of Progressive Glioblastoma.  Journal of Neuro-oncology, 118: 501-555, 2014.

Olson JJ, Nayak L, Ormond DR, Wen PY, Kalkanis SN:  The Role of Targeted Therapies in the Management of Progressive Glioblastoma.  Journal of Neuro-oncology, 118: 557-599, 2014.

Owonikoko T, Arbiser J, Zelnak A, Shu HK, Shim H, Robin A, Kalkanis SN, Whitsett T, Salhia B, Tran N, Ryken T, Moore M, Egan K, Olson JJ:  Current approaches to the treatment of metastatic brain tumours.  Nature Rev Clin Oncol, 11, 203–222, 2014. 

Shim H, Li W, Holder CA, Guo Y, Hu XP, Miller AH, and Olson JJ:  Use of high resolution volumetric MR spectroscopic imaging in assessing treatment response of GBM to an HDAC inhibitor. American Journal of Roentgenology. 203:W158-W165. DOI 10.2214/AJR.14.12518, 2014.

Bellail AC, Olson JJ and Hao C:  SUMO1 modification stabilizes CDK6 protein and drives the cell cycle and glioblastoma progression.  Nature Communications, June 23, 2014, 5:4234 | DOI: 10.1038/ncomms5234. 

Patel KR, Prabhu RS, Kandula S, Oliver DE, Kim S, Hadjipanayis C, Olson JJ, Oyesiku N, Curran WJ, Khan MK, Shu HK, Crocker I. Intracranial control and radiographic changes with adjuvant radiation therapy for resected brain metastases: whole brain radiotherapy versus stereotactic radiosurgery alone. J Neurooncol. 2014 Sep 5. [Epub ahead of print] PMID: 25189789

Linskey ME, Olson JJ, Mitchell LS, Kalkanis SN:  Clinical practice guidelines in the AANS/CNS Section on Tumors:  Past, Present and Future Directions.  Journal of Neuro-Oncology: 119: 557-568, 2014.

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Skull Base Surgery: Basic Techniques. Moore CE, Olson JJ (eds.), Plural Publishing, San Diego, CA, 2010.

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Book Chapters:

(Selected  from 8 chapters)

Ormond DR, Bouras A, Moore M, Gary M, Province P, Prabhu R, Egan KM, Rangaraju S, Appin, C, Hadjipanayis C, Nabors B, Voloschin A, Olson JJ:  Central Nervous System and Peripheral Nerve Tumors in Gansler T (ed) American Cancer Society Textbook of Cancer, Accepted February 20, 2014, In Press. 

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