Emory Winship Cancer Institute is recruiting patients through December, 2007 to particpate in a clinical trial of 3D digital mammography. The trial, which targets women with a high risk factor for development of breast cancer, compares a standard digital mammogram with the research stereoscopic or three-dimensional (3D) digital mammogram. 

The primary goal of the study is to evaluate this new technique for improved early detection of breast cancer. Two thousand women will receive screening mammograms using both techniques.  The research 3D mammogram is free to study participants.

Personal risk factors (any of the following):

• Personal history of breast and/or ovarian cancer, regardless of age
• Prior breast biopsy that included any of the following high risk, benign lesions, regardless of age:
• Lobular carcinoma in-situ
• Atypical lobular hyperplasia
• Atypical ductal hyperplasia
• Atypical columnar hyperplasia
• Positive test for known mutations of BRCA 1 or 2 genes, regardless of age.
• History of chest irradiation for treatment of non-breast disease (EX: lymphoma, lung cancer) at least 15 years prior to enrollment.

Family history (over 30 years of age with any of the following, some exceptions may apply)

• Ashkenazi Jewish ancestry, regardless of age
• Any history of male breast cancer on the maternal or paternal side
• Breast and ovarian cancer in a close relative (mother, sister, daughter)
• Breast or ovarian cancer in more than one close relative (mother, sister, daughter)
• Breast cancer in a close relative (mother, sister, daughter) with early onset (<50 years of age)
• Breast and ovarian cancer in a 2nd degree relative (grandmother, aunt, niece) with early onset of breast cancer (<50 years of age)
• Multiple history of breast cancer in 1st and 2nd degree relatives