Christian Larsen, MD,Phl
Emory ClinicEmory Healthcare Network Physician
At a Glance Toggle
- 1986 Started practicing
- 30 Years experience
- 5 OFFICE LOCATIONS
- 1 HOSPITAL AFFILIATION
About Dr. Larsen
In 2003, he performed the first islet transplant in Georgia. In addition to maintaining this busy surgical and clinical schedule throughout his career, he has built one of the foremost transplantation immunology programs in the world.
Dr. Larsen was the first to demonstrate the migration of Dendritic cells, so-called sentinels of the immune system, from the transplanted organ to the draining lymph node or spleen, where they initiate the immune response that causes allograft rejection. In a seminal publication in Nature in 1996, he provided unequivocal evidence that blocking T lymphocyte costimulation at the time of transplantation guarantees long-term survival of organ allografts in rodents. These findings were rapidly translated by Dr. Larsen's research group to primates and later to humans, and are currently a clinically proven treatment for recipients of solid organ transplants.
His current scientific endeavors are focused on achieving immunological tolerance through the induction of mixed hematopoietic chimerism and on the application of costimulation blockers to facilitate transplantation of insulin-producing cells, islets, to treat type 1 diabetes.
Dr. Larsen's achievements are distinguished by his talent to successfully drive a discovery from the bench to the bedside using the rigor of the scientific method.