Specialties

Neurosurgery (Board certified since 1998)

At a Glance

  • 1993 Started practicing
  • 24 Years experience
  • 1 OFFICE LOCATION
  • 2 HOSPITAL AFFILIATIONS

About Dr. Oyesiku

Dr. Oyesiku’s clinical and research focus is the surgical treatment and molecular biology of pituitary tumors. Dr Oyesiku has performed more than 1.500 surgeries for pituitary tumors and is one of a few surgeons in the U.S. and worldwide (and the first in Georgia) utilizing advanced 3-D endoscopic surgery for resection of pituitary tumors. This technology provides the surgeon with improved spatial resolution making surgery safer.

Dr. Oyesiku partners with Adriana Ioachimescu, MD, PhD, and a team of clinicians who collaborate in the diagnosis and treatment of patients with pituitary tumors at Emory’s Pituitary /Neuroendocrine Center. The Emory Pituitary/NeuroendocrineCenter has a nationwide and worldwide referral base and provides patients with comprehensive and personalized medical and surgical management of pituitary disorders. Specialists in Endocrinology, Neurosurgery, Neuroradiology, Neurophthalmology, Radiation Oncology, and ENT collaborate to provide state-of-the-art as well as novel advances in care and translational research.

Dr. Oyesiku is also Director of the Laboratory of Molecular Neurosurgery and Biotechnology, which is dedicated to unraveling pituitary tumorigenesis The Laboratory’s Pituitary Tumor Bank and Database allows clinicians and researchers to provide patients with advanced molecular biological analysis of their tumors. The laboratory was the first to identify unique aspects of pituitary adenoma gene expression and was the first to discover a key molecular marker for nonfunctional pituitary tumors that has enhanced the understanding of these tumors. Dr. Oyesiku and his team of researchers also developed a new modality for imaging pituitary tumors. This molecular imaging diagnostic tool was pioneered and first utilized at Emory for patients with pituitary tumors. The molecular imaging allows doctors to identify a key tumor marker in patients with clinically non functional pituitary tumors noninvasively, thereby identifying potential patients for a new targeted chemotherapy. The research team is currently undertaking this potentially groundbreaking new drug therapy for nonfunctional tumors that could lead to the first drug therapy for clinically nonfunctional pituitary tumors. To date, there has been no medical therapy available for patients with clinically non functional tumors.

My Clinical Interests

  • acoustic neuroma
  • brain injury
  • brain surgery
  • brain tumors
  • carpal tunnel syndrome
  • cerebral edema
  • chiari malformations
  • cranial nerve disorder
  • Cushing's disease
  • endoscopy
  • hemangioma
  • hydrocephalus
  • microsurgery
  • microvascular surgery
  • muscle and nerve biopsy
  • neuroendocrine
  • neuroendoscopy
  • peripheral nerve surgery
  • pituitary tumor
  • skull base tumors
  • Spine Tumor
  • stereotactic surgery
  • trigeminal neuralgia

Academic Profile

Training

MEDICAL SCHOOL

University of Ibadan, Ibadan, Nigeria

INTERNSHIP

University of Lagos, Lagos, Nigeria

Hartford Hospital, Hartford, CT

RESIDENCY

Emory University Hospital, Atlanta, GA

FELLOWSHIP

Lankenau Hospital, Wynnwood, Philadelphia

Hartford Hospital, Hartford, CT

Professional Memberships

American Association for the Advancement of Science

American Association of Neurological Surgeons

American College of Surgeons

American Medical Association

Atlanta Medical Association

Brain Injury Association of Georgia

Congress of Neurological Surgeons

Georgia Neurosurgical Society

Georgia State Medical Association

MENSA International

Medical Association of Atlanta

Medical Association of Georgia

National Medical Association

New York Academy of Sciences

Society for Neuroscience

Society for Neurotrauma

Southern Medical Association

Southern Neurosurgical Society

World Federation of Neurosurgical Societies

Languages spoken

  • Yorubia

Honors & Awards

AANS/CNS Joint Section of Neurotrauma
America's Top Surgeons

Best Doctors
Marquis Who's Who in America

Young Investigator Award
Brain Trauma Foundation

Major Publications

Combined transsphenoidal and pterional craniotomy approach to giant pituitary tumors. Surgical Neurology,57:380-390, 2002.

Differential Expression of Folate Receptor in Pituitary Adenomas. Cancer Research,63:4218-4224, 2003.

Exploratory study of 99mTc-EC20 imaging for identifying patients with folate receptor-positive solid tumors. J Nucl Med. 2008 Jun;49(6):899-906,Epub 2008 May 15.

Folate receptor alpha regulates cell proliferation in mouse gonadotroph alphaT3-1 cells. Exp Cell Res. 2009 Nov 1;315(18):3125-32,Epub 2009 May 14.

Folate receptor expression in pituitary adenomas cellular and molecular analysis. Vitam Horm. 2008,79:235-66.

Guidelines for Management of Acute Cervical Spinal Injuries. Neurosurgery,50:S1-6, 2002.

Intracranial Arteriovenous Malformations Treated Utilizing a Linear Accelerator-Based Patient Rotator or Commercially Available Radiosurgery System. Stereotactic and Functional Neurosurgery,83:91-100, 2005.

Intrasellar Pituitcytoma in a patient with other endocrine neoplasms. Archives of Pathology and Labatory Medicine,125:527-530.

Novel Molecular Signaling in Human Clinically Non-Functional Pituitary Adenomas by Gene Expression Profiling. Proceedings of the 13th World Congress of Neurological Surgery, Marrakech, Morocco, Medimond International Proceedings,1151-1156, 2005.

Novel patterns of gene expression in pituitary adenomas identified by cDNA microarrays and quantitative RT-PCR. Journal of Clinical Endocrinology and Metabolism,86:3097-3107, 2001.

Precipitating factors in pituitary apoplexy. Journal of Neurology, Neurosurgery, and Psychiatry,71:542-545, 2001.

Progesterone and llopregnanolone Reduce Inflammatory Cytokines after Traumatic Brain Injury. Experimental Neurology,189:404-412, 2004.

Proteomics and transcriptomics analyses of secretagogin down regulation in human non-functional pituitary adenomas. Pituitary,6: 189-202, 2004.

SPECT/CT of FolateScan ( Tc-99m EC20) in pituitary tumors: A novel imaging tracer and Technique. Journal of Nuclear Medicine,Vol 45 (5 S) 368P, 2004.

Screening for MENI Tumor Suppressor Gene Mutations in Sporadic Putuitary Tumors. Journal of Endocrinological Investigation,23:304-309.

Locations & Appointments

1 Office Location(s)

1

Emory Clinic, Bldg B

Emory Clinic at 1365 Clifton Rd
1365 Clifton Rd NE
Atlanta, GA 30322
  • 404-778-5770
S

2 Hospital Affiliation(s)

2

Emory University Hospital

1364 Clifton Rd NE
Atlanta, GA 30322
H
3

Emory University Hospital Midtown

550 Peachtree St NE
Atlanta, GA 30308
H

Academic Profile

Training

MEDICAL SCHOOL

University of Ibadan, Ibadan, Nigeria

INTERNSHIP

University of Lagos, Lagos, Nigeria

Hartford Hospital, Hartford, CT

RESIDENCY

Emory University Hospital, Atlanta, GA

FELLOWSHIP

Lankenau Hospital, Wynnwood, Philadelphia

Hartford Hospital, Hartford, CT

Professional Memberships

American Association for the Advancement of Science

American Association of Neurological Surgeons

American College of Surgeons

American Medical Association

Atlanta Medical Association

Brain Injury Association of Georgia

Congress of Neurological Surgeons

Georgia Neurosurgical Society

Georgia State Medical Association

MENSA International

Medical Association of Atlanta

Medical Association of Georgia

National Medical Association

New York Academy of Sciences

Society for Neuroscience

Society for Neurotrauma

Southern Medical Association

Southern Neurosurgical Society

World Federation of Neurosurgical Societies

Languages spoken

  • Yorubia

Honors & Awards

AANS/CNS Joint Section of Neurotrauma
America's Top Surgeons

Best Doctors
Marquis Who's Who in America

Young Investigator Award
Brain Trauma Foundation

Major Publications

Combined transsphenoidal and pterional craniotomy approach to giant pituitary tumors. Surgical Neurology,57:380-390, 2002.

Differential Expression of Folate Receptor in Pituitary Adenomas. Cancer Research,63:4218-4224, 2003.

Exploratory study of 99mTc-EC20 imaging for identifying patients with folate receptor-positive solid tumors. J Nucl Med. 2008 Jun;49(6):899-906,Epub 2008 May 15.

Folate receptor alpha regulates cell proliferation in mouse gonadotroph alphaT3-1 cells. Exp Cell Res. 2009 Nov 1;315(18):3125-32,Epub 2009 May 14.

Folate receptor expression in pituitary adenomas cellular and molecular analysis. Vitam Horm. 2008,79:235-66.

Guidelines for Management of Acute Cervical Spinal Injuries. Neurosurgery,50:S1-6, 2002.

Intracranial Arteriovenous Malformations Treated Utilizing a Linear Accelerator-Based Patient Rotator or Commercially Available Radiosurgery System. Stereotactic and Functional Neurosurgery,83:91-100, 2005.

Intrasellar Pituitcytoma in a patient with other endocrine neoplasms. Archives of Pathology and Labatory Medicine,125:527-530.

Novel Molecular Signaling in Human Clinically Non-Functional Pituitary Adenomas by Gene Expression Profiling. Proceedings of the 13th World Congress of Neurological Surgery, Marrakech, Morocco, Medimond International Proceedings,1151-1156, 2005.

Novel patterns of gene expression in pituitary adenomas identified by cDNA microarrays and quantitative RT-PCR. Journal of Clinical Endocrinology and Metabolism,86:3097-3107, 2001.

Precipitating factors in pituitary apoplexy. Journal of Neurology, Neurosurgery, and Psychiatry,71:542-545, 2001.

Progesterone and llopregnanolone Reduce Inflammatory Cytokines after Traumatic Brain Injury. Experimental Neurology,189:404-412, 2004.

Proteomics and transcriptomics analyses of secretagogin down regulation in human non-functional pituitary adenomas. Pituitary,6: 189-202, 2004.

SPECT/CT of FolateScan ( Tc-99m EC20) in pituitary tumors: A novel imaging tracer and Technique. Journal of Nuclear Medicine,Vol 45 (5 S) 368P, 2004.

Screening for MENI Tumor Suppressor Gene Mutations in Sporadic Putuitary Tumors. Journal of Endocrinological Investigation,23:304-309.