Research & Clinical Trials

Observational, Post-Marketing Renal Safety Surveillance Registry in Patients with Chronic Hepatitis B (HBV) Infection with Decompensated Liver Disease Receiving Nucleotide/side Therapy (Gilead HBV Registry)
Principal Investigator: James R. Spivey, MD
Lead Coordinator: Shine Thomas, RN

A Multi-Center, Randomized, Prospective, Open-Label Phase III Study to Evaluate the Efficacy, Safety and Pharmacokinetics of Hepatitis C Immune Globulin (HCIG), in Orthotopic Liver Transplant Recipients (Biotest 988)
Principal Investigator: James R. Spivey, MD
Lead Coordinator: Maria Imelda Browne, RN

HCV-TARGET: Hepatitis C Therapeutic Registry and Research Network, A Longitudinal, Observational Study (HCV Target)
Principal Investigator: James R. Spivey, MD
Lead Coordinator: Carole Seeley, RN

A Phase II Randomized Multicenter Placebo- Controlled Blinded Study of Sorafenib Adjuvant Therapy in High Risk Orthotopic Liver Transplant (OLT) Recipients with Hepatocellular Carcinoma (HCC)
Principal Investigator: Stuart J. Knechtle, MD
Lead Coordinator: Brianna Cheatham, RN

Treatment of Drug Overdose and Poisonings with the Molecular Adsorbent Recirculating System (MARS) – chart review study
Principal Investigator: Ram Subramanian, MD
Lead Coordinator: Elizabeth Ferry, RN

ALFSG-OCR-002: A Phase 2a Study to Evaluate the Safety and Tolerability of OCR-002 (ornithine phenylacetate) in the Treatment of Patients with Acute Liver Failure/Severe Acute Liver Injury (STOP-ALF)
Principal Investigator: Ram Subramanian, MD
Lead Coordinator: Rivka Elbein, RN

A Multi-Center Group to Study Acute Liver Failure (AlFSG)
Principal Investigator: Ram Subramanian, MD
Lead Coordinator: Rivka Elbein, RN

A Multi-Center, Double-Blind, Randomized, Controlled Study to Determine the Safety and Pharmacokinetics of Ifetroban Injection in Hepatorenal Syndrome
Principal Investigator: Ram Subramanian, MD
Lead Coordinator: Sallie Carpentier, RN

Multicenter, Randomized Phase 2B Study to Evaluate the Efficacy, Safety and Tolerability of OCR-002 (ornithine phenylacetate) in Hospitalized Patients with Cirrhosis and Associated Hyperammonemia with an Episode of Hepatic Encephalopathy (STOP-HE Study)
Principal Investigator: Ram Subramanian, MD
Lead Coordinator: Sallie Carpentier, RN

A Randomized, Open-Label, Multicenter, Controlled Study to Assess Safety And Efficacy of ELAD In Subjects With Alcohol-Induced Liver Decompensation (ELAD 208)
Principal Investigator: Ram Subramanian, MD
Lead Coordinator: Natasha Jones, RN

Protocol for Tracking Economic Data of Subjects Participating in Protocols VTI-208, VTI-210 or VTI-212.(ELAD 210)
Principal Investigator: Ram Subramanian, MD
Lead Coordinator: Natasha Jones, RN

Infections in Cirrhosis: A Prospective Multi-Center Study
Principal Investigator: Ram Subramanian, MD
Lead Coordinator: Natasha Jones, RN

If you are interested in learning more about these or other Emory Transplant Center Clinical Research projects, please call the ETC Clinical Research Program at 404-712-1114 to speak with one of our research coordinators.

Emory Transplant Center