Male infertility has a wide range of causes, from physical blockages to hormone disruptions to lifestyle factors and environmental exposures.
Some common risk factors for male infertility include:
- Varicocele
- Lifestyle factors like smoking, and alcohol or cannabis use
- Obesity
- Certain medications
Varicocele — an enlargement of veins within the scrotum — is one of the most common. Dr. Mehta describes it as “a varicose vein of the testicle” and notes that it can impair sperm production, sperm quality or both. “Varicoceles are extremely common, and the good news is they are also highly treatable,” she says.
Lifestyle factors contribute to fertility
Lifestyle factors matter as well, though they are often misunderstood. Alcohol, for example, doesn’t have to be eliminated entirely, but heavy or frequent drinking can interfere with sperm production. Cannabis use, especially when regular, has also been linked to reduced sperm count and motility. Cigarette smoking is linked to higher risk of miscarriage.
“We’re learning more and more about how social habits affect male fertility,” Dr. Mehta says. “It’s something I always ask patients about, because reducing or stopping smoking, alcohol and cannabis use can make a measurable difference.”
Obesity is another contributor, and one that is increasingly common. Extra adipose tissue (fat) can alter hormone levels, raise body temperature around the testicles and increase inflammation — all of which can impair fertility. Meanwhile, certain medications, from testosterone supplements to some antidepressants and prostate medications, can also interfere with sperm production or ejaculation.
But just as important, Dr. Mehta stresses, is what not to assume. “Having a risk factor does not mean fertility is impossible,” she says. “And lacking obvious risk factors doesn’t guarantee everything is normal. That’s why testing is so important — it removes guesswork.”